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العنوان
Synthesis of some heterocyclic compounds with
anticipated biological activity/
المؤلف
Mansour, Salma Yehia Mohamed EL-Sayed.
هيئة الاعداد
باحث / Salma Yehia Mohamed EL-Sayed Mansour
مشرف / Galal Hosni Sayed
مشرف / Magda Ismail Marzouk
مناقش / Mohamed Said Abdelhalim
تاريخ النشر
2021.
عدد الصفحات
409p. :
اللغة
الإنجليزية
الدرجة
الدكتوراه
التخصص
الكيمياء
تاريخ الإجازة
1/1/2021
مكان الإجازة
جامعة عين شمس - كلية العلوم - الكمياء
الفهرس
Only 14 pages are availabe for public view

from 397

from 397

Abstract

First part:
The starting chalcone 3 was prepared via the reaction of 4-
acetyl biphenyl (1) with 4-(dimethyl amino) benzaldehyde (2) in
ethanol in the presence of sodium hydroxide.
Nicotinonitrile derivative 4 has been synthesized by one pot
reaction of 4-acetyl biphenyl (1), 4-(dimethyl amino) benzaldehyde
(2) and malononitrile in the presence of ammonium acetate under
microwave irradiation, which on reaction with hydrazine hydrate
afforded the pyrazolopyridine derivative 5 (Scheme1).