الفهرس | Only 14 pages are availabe for public view |
Abstract Mycotoxins are toxic secondary metabolites of fungi that usually belong to one of three genera Aspergillus, Penicillium or Fusarium. Mycotoxins may be produced on a wide range of agricultural commodities under a diverse range of conditions. Mycotoxins consumed through food can be very harmful to humans and animals.The adverse health effects of mycotoxins range from acute poisoning to long-term effects such as immune deficiency and cancer. The mycotoxins affect a quarter of the world’s food crops each year, including many basic foodstuffs and animal feed, as well as crops. Such effect occurs most prominently in hotter countries where food shortages may already be a problem. In this thesis, two mycotoxins were studied : Zearalenone (ZEA) is a mycotoxin created by a range of Fusarium fungi that infects cereals. ZEA prompts reproductive toxicity due to its strong estrogenic effects. Deoxynivalenol (DON), a mycotoxin produced mainly by Fusarium graminearum in contaminated food, is assumed to cause several outbreaks of gastrointestinal disorder among humans. The development of an accurate analytical method for the detection of mycotoxins is highly needed to satisfy food safety requirement. In this work, we present different techniques for determination of ZEA and DON in food samples using Carbon nanotubes (CNTs) , Molecularly imprinted polymers (MIPs) , and Metallophthalocyanines (MPcs. |