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This case control study was conducted to evaluate the effect of clostridium on body composition and anthropometric parameters in autistic children and to assess the correlation between the percentage of clostridium and the behavioral changes among autistic children
Sixty children were retrospectively recruited. Thirty of them were autistic (20 males and 10 females), while thirty were normal children (20 male and 10 female). The age ranged from 3-10 yrs., the mean age in cases was 5.07±1.95
All patients were subjected to: Diagnosis of autism by detailed history, Diagnostic Interview Revised (ADI-R), Childhood autism rating scale (CARS), measurements of body composition and anthropometric parameters as body Weight (Wt), body Height (Ht) and head circumference. Detection of Clostridium in stool samples by quantitative real-time PCR.
The results revealed, when comparing Autistic children with non-autistic children as regard anthropometric parameters, there appears to be statistically significant difference between two groups according to z Wt. and z Ht.
Moreover, when comparing between Autistic and non-autistic children as regarding the presence of six different species of Colistridium Bacteria, there was statistically significant difference between two groups as regard Difficile, Paraputrificum, Clostridioforme, Bolteae and Tertium.
However, when correlated between the six species of bacteria and CARS, ADIR there was no statistically significant relation.
When comparing the six species of bacteria with anthropometric parameters in autistic children (cases) there were statistically significant correlation between clostridioforme with BSF,SUSF and W/H.