الفهرس 
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Abstract
This Cross Sectional observational Study was conducted on 60 prevalent hemodialysis patients in El-Zaytoun Specialized Hospital and Mansheyet El-Bakry General Hospital. Informed consent was taken from every participants. Patients were divided into 3 equal groups:
group I: 20 patients have known history of intradialytic hypotension and HCV seropositive.
group II: 20 patients have known history of intradialytic hypotension and HCV seronegative.
group III: 20 patients have No history of intradialytic hypotension.
Intradialytic hypotension defined as a decrease in systolic blood pressure by ≥20 mm Hg or a decrease in MAP by 10 mm Hg associated with symptoms that include: abdominal discomfort; yawning; sighing; nausea; vomiting; muscle cramps; restlessness; dizziness or fainting; and anxiety (KDOQI 2005).
Average age was 58 ±14 years. Male patients were 33 (55%). Mean hemodialysis duration was 60 ±27 months. Mean ultrafiltration rate was 8.24 ± 1.56 ml/kg/hr. Hypertension was the main cause of ESRD.
NO before session was significantly higher in patients in group I and group II, but not in group III (76.26 ±31.64 vs. 48.91 ± 20.42 mol/L). Those are patients with history of IDH, and they had higher NO in the first measurement.
NO level before session in group I was significantly higher than group II and group III. This could show that seropositive hepatic patients have higher NO in their blood, even before start of Hemodialysis session. No significant difference between group II and group III. (88.66 ± 31.94 vs. 63.87 ± 26.68 vs. 48.91 ± 20.42 mol/L in groups I, II, III respectively) (p value = 0.000).
NO level dropped both in group I and group II. group III were not tested, because they didn’t develop IDH. However, NO level in group I was significantly higher than group II (63.48 ± 33.93 vs. 40.72 ± 13.15mol/L) (p value = 0.008).
Serum Na+ level was significantly higher in group III, as compared to group I and group II (136.25 ± 3.91, vs 136.7 ± 2.62, vs 138.75 ± 2.55 in groups I, II, III respectively) (p value = 0.03).