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العنوان
Evaluation of the role of post-operative Antibiotics Use after Lower Limbs Varicose Veins’ Conventional Surgery as a Prophylactic Measure against Surgical Site Infection \
المؤلف
Okaz, Mahmoud Abdel Hamid.
هيئة الاعداد
باحث / محمود عبد الحميد عكاز
مشرف / خــالد زكــى منصــور
مشرف / ناصر السعيد حماد
مشرف / هانى رفيق واكيم
تاريخ النشر
2019.
عدد الصفحات
148 p. :
اللغة
الإنجليزية
الدرجة
ماجستير
التخصص
جراحة
تاريخ الإجازة
1/1/2019
مكان الإجازة
جامعة عين شمس - كلية الطب - الجراحة العامة
الفهرس
Only 14 pages are availabe for public view

from 148

from 148

Abstract

Lower limb varicose veins (VV) is considered to be one of the most prevalent diseases in vascular surgery with prevalence rates estimated to be around 23% of the USA population and higher rates are found in developing countries.
These figures show that VV is a healthcare problem with significant morbidity and healthcare costs, by all means of treatment whether it is surgical ligation and stripping, endovenous ablation or injection sclerotherapy.
Surgical site infections (SSIs) on the other hand are considered to be one of the most serious and cumbersome surgical complication of many surgical operations causing increase in morbidity, mortality and hospital stay period.
Examples of risk factors for developing SSIs are immunocompromised status, Diabetes, Obesity and prolonged operation time.
Measures to reduce SSIs are mainly focused on the proper skin preparation of the surgical area, perioperative strict glycemic control, and suitable perioperative antimicrobial prophylaxis and avoid unnecessary hair shaving.
Little evidence is present to support the benefit of using postoperative systemic antibiotic regimen in clean operations such as GSV stripping and ligation, as a matter of fact it may increase the presence of antibiotic resistant strains of bacteria
This study aimed to evaluate the role of using post-operative antibiotics after varicose veins conventional surgery as a prophylactic measure against SSI.
It was a prospective randomized study conducted on cases scheduled for conventional VV surgery to compare using a single dose IV antibiotic at induction of anesthesia only versus using systemic antibiotics at induction of anesthesia and postoperatively. The study started in September 2018 and continued till the total number of patients (60 patients) was recruited in the study in July 2019. The study setting was at Ain Shams University and El Maadi Military hospital vascular surgery departments. Patients were randomized into two groups one that didn’t use post-operative antibiotics (group A) and the other used pre and post-operative antibiotics (group B).
Patients with high risk factors for developing SSI were excluded so that we can clearly show the relation between using post-operative antibiotics and occurrence of SSI.
The mean age of all patients was (35.1 ± 8) years. Regarding gender of the patients, the majority (68.3%) of patients was females. the mean BMI of all patients was (23.8 ± 3.4).
Regarding post-operative end-points, 17 patients (28.3%) had hematoma, 3 patients (5%) had surgical site infection and thrombophlebitis. Out of the three patients that had SSI, two were in group A (6.7%) and one was in group B (3.3%).
Hematoma occurred in 10 patients in group A (33.3%) and 7 patients in group B (23.3%) while thrombophlebitis occurred in 3 patients all of which were in group B (10%)
There was non-significant statistical correlation between using post-operative antibiotics and SSIs.
Regarding hematoma and thrombophlebitis there was no significant statistical correlation between them and using post-operative antibiotics.