الفهرس 
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Abstract
Patients with Paget’s disease of the breast have a high incidence of an underlying breast carcinoma. Most of the patients in this study presented had positive mammogram and sonography.
Mammography and sonography should be performed to identify the underlying breast carcinoma.
Those who have only nipple areolar changes without a palpable mass have less positive mammography and less invasive carcinoma.
At Ain Shams university hospitals patients having pagetoid cells by biopsy and no mass radiologically will undergo simple mastectomy and if pathology proved any malignancy in breast tissue axillary clearance will be done and may be followed by radiotherapy.
Patients having pagetoid cells by biopsy and a mass radiologically which is invasive or insitu with microinvasion will undergo modified radical mastectomy and may be followed by radiotherapy. But if pagetoid cells and mass radiologically which is in situ simple mastectomy will be done.
Hormonal treatment is scheduled according to receptor status of the tumors.