الفهرس 
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Abstract
Tilapia is a worldwide commercially important fish and is recognized as one of the most important species of aquaculture in the 21st century. Total tilapia production in the world was 3.49 million tons in 2010. Nile tilapia (O. niloticus) is considered as an important fish - farming species in Egypt.
This study aimed to evaluate the effects of phytobiotic in the form Echinacea purpurea or probiotic as lactobacillus acidophillus in comparison with prebiotic in the form β-glucan on growth performance, some biochemical, hematological , immunological parameters and genes expression in Nile tilapia (Oreochromis niloticus). A total of 240 Nile tilapia with an average body weight of 25.02 ± 0.01g were assigned at random to 4 groups with 3 replicates (20 per replicate). Dietary treatments consisted of basal diet with no additives (group1 as control), 0.75g /kg diet of Echinacea extract (group 2), Lactobacillus acidophilus7x106 cell-100g (group 3) and 1 g/kg β-glucan (group 4). At 4 th, 8th and 12th week of feeding trial.
After statistical analysis our results referred to the following:
Weight of Nile tilapia:
All groups after 4, 8 and 12 weeks of feeding experiment (phytobiotic in the form Echinacea purpurea, probiotic as lactobacillus acidophillus and prebiotic in the form β-glucan) showed higher growth performance than those fed the control diet.
The growth performance (Specific growth rate and body weight gain) of fish fed different diets was higher than those fed the control diet and best group was with that fed Echinacea supplemented extract.