الفهرس 
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Abstract
The fact that several heterocyclic compounds containing benzoxazole moiety exhibitedpotent anti-breast cancer activity through different mechanisms of action promoted the designand synthesis of new benzoxazole derivatives as potential cytotoxic agents against MCF-7and MDA-MB-231 breast cancer cell lines.
The designed compounds contained the corenucleus 2-phenyl benzoxazole moiety substituted at the 4-position of the phenyl ring with different substituents including flexible side chains, 5-membered heterocycles or fusedheterocyclic systems.Studies on the synthesis of the designed compounds, their spectral analysis as well astheir evaluation for cytotoxicity, are presented as the main text of this thesis.