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العنوان
RISK FACTORS FOR MBT SHUNT THROMBOSIS
المؤلف
Abouhashim, Sherihan Wagdi Muhammad.
هيئة الاعداد
باحث / شيريهان وجدي محمد أبوهاشم
مشرف / شريف السيد عزب
مشرف / أشرف عبدالحميد الميداني
مشرف / أيمن عبدالله سليمان
تاريخ النشر
2019.
عدد الصفحات
115 p. :
اللغة
الإنجليزية
الدرجة
ماجستير
التخصص
أمراض القلب والطب القلب والأوعية الدموية
تاريخ الإجازة
1/1/2019
مكان الإجازة
جامعة عين شمس - كلية الطب - جراحة القلب والصدر
الفهرس
Only 14 pages are availabe for public view

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Abstract

A modified Blalock-Taussig shunt (MBTS) is a surgically placed graft between the systemic and pulmonary arterial circulations that redirects systemic blood flow into the pulmonary circulation. It is often placed in Neonates and infants with right-sided obstructive cardiac defects to increase pulmonary blood flow.
The MBT shunt provides the possibility to create pressure- and volume-controlled pulmonary perfusion with preservation of distal flow in the subclavian artery. It has extended the surgical options in the treatment of children with cyanotic heart disease, many complications of the MBT shunt are reported such as thrombosis, infection, and pseudo aneurysm of the graft.
A prospective study of patient was enrolled to 45 cases of various types of Cyanotic heart diseases who had undergone MBTS creation from February 1/2018 to end of February, 2019.
After collecting data, we found that developed shunt occlusion around one quarter or less out of the studied cases and around three quarter or less passed successfully with patent shunt flow, those patients studied regarding to different parameters and diagnosed by Clinical assessment, echocardiography and laboratory tests were collected and Patients were followed up on their early post-operative period.
MBT shunt occlusion was significantly associated with several factors including young age at the time of surgery, high level of hematocrit level after operation, thoracotomy surgical approach, use of heparin intra-operatively and size of PTFE shunt, nor-adrenalin also showed relation with shunt occlusion as a consequence of poor hemodynamic state during and after operation in which we found that all of patients who had shunt occlusion received nor-adrenalin infusion after operation as well as inotropes in which two third of patients whose developed shunt occlusion during operation or even post-operatively, with no statistical significance with other studied variables.
Regarding to mortality we found that more than one third of the study patients have died, most of them are male, less than six months of age, weigh five kg or less, desaturated with oxygen < 60% prior to operation and sternotomy surgical approach were factors associated with postoperative mortality. There was a statistical significance between young age at the time of operation (less than six months) and mortality, as well as use of nor-adrenalin in which all dead patients received nor-adrenalin.