الفهرس 
ANATOMY OF CORONARY VESSELSOnly 14 pages are availabe for public view
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Abstract
Coronary artery disease remains a major cause of morbidity and mortality. Reducing the prevalence of CAD, morbidity and mortality related to it, is an important public health goal due to the significant disease burden.
It has been emphasised by many studies that CCTA has good correlation with IVUS in the quantitative plaque analysis. The ability to interpret CCTA images beyond the lumen stenosis degree is of utmost importance so as to develop personalized medical care and enable therapeutic interventions on the basis of plaque characteristics.
The probability of a plaque to rupture and to cause vessel obstruction and then subsequently myocardial infarction is known to be dependent on its composition.
The burden of coronary calcification quantified by CCTA is considered a strong predictor of CAD, However, CAC score alone will not accurately reflect the vessels atherosclerotic burden due to the modifiable noncalcified plaques.
The absence of coronary calcification does not exclude obstructive CAD or the need for clinically indicated coronary revascularization among patients with a high enough suspicion of CAD prompting an indication for CCTA.
In the present study, we found that, noncalcified plaques were more prevalent than calcified plaque in younger individuals. And that males show a statistically significant higher incidence of multivessel affection than females. Diabetic patients have higher incidence of multivessel affection than nondiabetic patients. And LAD is the most common diseased coronary vessel.
In conclusion:
Multi-slice CT coronary angiography is the non-invasive technique for plaque analysis, it is a reliable method to detect CAD and estimate the degree of stenosis, number of diseased arteries and different pattern of their affection.
Using automated software provide the major advantage of highly reproducible assessments of lumen area, minimal lumen diameter, plaque burden, plaque volume and can be used in following the response to therapy. And also allowing faster quantifications, which make them eligible for more widespread use.