الفهرس 
PREECLAMPSIIA CLASSIIFIICATIION AND TERMIINOLOGY
RIISK FACTORS OF PREECLAMPSIIAOnly 14 pages are availabe for public view
Abstract
Aim: This prospective study aims to investigate the
serum concentrations of CA-125 in normal and preeclamptic
pregnancies and thus to specify the value of this biochemical
marker in prediction and diagnosis of preeclampsia.
Methods: This study reviews a total of 72 primigravid
women with singleton pregnancy. These participants were
categorized into two groups: control (n = 36) and preeclampsia
(n = 36).
Results: Serum CA-125 concentrations were found to
correlate positively with diastolic blood pressure (r = 0.345, Pvalue
< 0.001) and maternal age (r = 0.052, P-value = 0.002)
but no significant correlation was found with systolic blood
pressure, platelet count and gestational age at time of delivery.
When the cut-off point for serum CA-125 concentration was
accepted as 51.38 IU/ml, the sensitivity and specificity of this
biochemical marker were, respectively, 63.9% and 97.2% for
the detection of preeclamptic pregnancies. On the other hand,
positive and negative predictive values for CA-125 were 95.8%
and 72.9%, respectively.
Conclusion: This study suggests that CA-125 is a
biochemical marker which reflects the underlying inflammatory
process in preeclampsia.
Keywords: CA-125 – Preeclampsia – Pregnancy .