الفهرس 
PainOnly 14 pages are availabe for public view
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Abstract
Hysterectomy is the most common major gynaecological operation and second most common surgery done after caesarean section all over the world.
Abdominal hysterectomy is associated with postoperative pain. Traditional methods for postoperative pain management include opioids administered systemically using patient-controlled intravenous analgesia (PCA), or neuroaxially via epidural or spinal injections. However, pain relief, specifically on movement, is not always adequately controlled when using PCA, despite moderate to large doses of morphine. This is associated with side-effects such as postoperative nausea and vomiting (PONV), tiredness, pruritus, headache, and constipation.
The major goal in postoperative pain management is to minimize the dose of medications and decrease side effects, while still providing adequate analgesia. Postoperative pain relief leads to earlier mobilization, shortened hospital staying, reduced hospital costs, and increased patient satisfaction.
The study aim to compare the effect of intravenous magnesuim sulfate versus intravenous diclofenac on postoperative analgesia in patients undergoing total abdominal hysterctomy.
The study was a single blinded randomized controlled clinical study.
The study was conducted in Ain Shams University Maternity Hospital from October 2017 to July 2018.
This study was performed on 60 patients who had undergone hysterectomy surgery. The patients were divided into two groups of 30 patients each based on a random number table: one receiving magnesium sulphate the other one receiving diclofenac. The mean age of the patients in group A was 49.97±5.31, and it was 51.50 ±6.13.in the study group B; there was no significant difference between them (p < 0.05) p=0.305. The mean BMI of the patients in group A was 27.45±2.13 Kg/m2, and it was 27.12±2.42 Kg/m2 in group B i.e., there was no significant difference between them (p < 0.05 p=0.470). Also the duration of surgery of all the patients was recorded the mean duration of surgery of group A was 104.77 ± 8.51 and that of group B was 102.90 ± 10.17 with p value = 0.444.
We concluded that IV preventive doses (low doses) of magnesium sulphate with dosage of 50 mg/kg in 100 mL of normal saline solution alleviate postoperative pain throughout the first day after TAH under balanced general anesthesia significantly and reduce opioid consumption as well.