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العنوان
THE RELATION BETWEEN SERUM
URIC ACID AND OBESITY IN
EGYPTIAN ADOLESCENTS /
المؤلف
ALI,MANAR BADR MOHAMED.
هيئة الاعداد
باحث / MANAR BADR MOHAMED ALI
مشرف / DR.HANAN EL SEBAIE EL-HEFNAWY
مشرف / HALA ABD EL- HADY SALEH
مشرف / DINA SHAWKY YASSIN EL-ZIFZAF
تاريخ النشر
2013
عدد الصفحات
203p.:
اللغة
الإنجليزية
الدرجة
ماجستير
التخصص
الروماتيزم
تاريخ الإجازة
1/1/2013
مكان الإجازة
جامعة عين شمس - كلية الطب - الطب الطبيعي والروماتيزم والتأهيل
الفهرس
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Abstract

Overweight and obesity are subjects of much public
health concern especially among children and adolescents
in different regions of the world .
Childhood obesity predisposes to type 2 diabetes ,
hypertension , hyperlipidemia , hepatic and renal diseases
and cardiovascular diseases .Hyperuricemia is one of the
laboratory abnormalities often seen in pediatric clinics.
Recently, greater attention has been focused on
Hyperuricemia in children, since several investigators
reported its association with life-style diseases .Some
studies have reported the incidence of hyperuricemia in
obese children. The aim of the study was to establish a
relationship between serum uric acid and weight in
Egyptian adolescents .
This study was conducted on 60 apparently healthy
early adolescent children aged 12-14 years , they have
been divided into three equal groups according to body
mass index for age percentiles obese adolescents ,
overweight adolescent and normal weight adolescents .
They were subjected to full medical history, thorough
clinical examination, laboratory investigation (including
serum uric acid and ALT) in addition to anthropometric
measurements which include weight, height, body mass
index , waist circumference and hip circumference .Our results showed that there was a statistically
significant difference between the three groups of
adolescents as regards the mean value of serum uric acid
as the obese and overweight adolescents showed higher
level of serum uric acid than the normal weight adolescents
.And there was a statistically significant positive
correlation between serum uric acid and waist
circumference and a high statistically significant positive
correlation between serum uric acid and weight , BMI and
hip circumference . The use of the multiple logistic
regression test to show predictors of hyperuricemia
revealed a significance of the use of waist circumference ,
hip circumference and waist to hip circumference as
predictors of hyperuricemia in adolescents and the waist
circumference was the best predictor of hyperuricemia with
sensitivity 76.4 % , specificity 74.4 % and Cut-off point =
91.50 .