الفهرس 
Insecticide UsedOnly 14 pages are availabe for public view
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Abstract
Fipronil belongs to a new class of phenylpyrazole group and is the relatively new yet, most widely used insecticide, having acknowledged for addressing issues related to insect resistance and public health hazards that are commonly encountered with conventional group of pesticide families. Majority of pesticides are known for disrupting biochemical and even possess tissue damaging propensities. The literature support for outcome of biochemical and histopathological disruption remains well established for organophosphates, organochlorines, and pyrethroids. However, similar toxicity effects have been rarely addressed for fipronil so far, which aggravated the need to gauge their impact on mammalian class. Furthermore, the studies suggesting the impeding effects on functioning of hepatic and renal tissues in a consolidated pattern are found to be very limited. Recently, researchers have expressed concern of potential adverse public health effects on account of widespread fipronil use in commercial and for home applications. There is comparatively little information available about action of fipronil in vertebrates. Fipronil is reported to be moderately toxic to rats and mice but highly toxic to aquatic invertebrates and fish. Fipronil induced neuronal cell death has been shown to be mediated by generation of reactive oxygen species (ROS) leading to apoptosis. Several researchers have expressed important environmental concern of fipronil exposure and stated that cyclic, systemic applications of fipronil have bioaccumulative effects which in turn.