الفهرس | Only 14 pages are availabe for public view |
Abstract Osteoporosis is a major public health problem and becoming increasingly prevalent with the aging of the world population. A major obstacle to combating osteoporosis is the failure to identify individuals with the condition until the clinical consequences have occurred. Thus the identification of risk factors for osteoporosis may facilitate access to diagnosis using DXA and to subsequent intervention. Malnutrition is a known risk factor affect bone metabolism and enhanced risk of osteoporosis. This cross sectional study was conducted in outpatient clinics in Ain Shams University hospital (geriatric and internal medicine) to investigate the relationship between osteoporosis and nutritional status as determined by the Mini-Nutritional Assessment questionnaire (MNA), and to assess the agreement of malnutrition risk between Malnutrition Universal Screening Tool (MUST) and Mini-Nutritional Assessment questionnaire (MNA) and to compare their relationship with osteoporosis. 200 postmenopausal women had completed the questionnaire that includes socio demographic characteristics, menstrual history, medical history, MNA and MUST. Also screening for osteoporosis using DXA scan was done. The majority of the participated females aged from 45 to 64 years (81%) only19% above 65.The majority of the studied females were married (83.5%), nonsmoker (89.5%), working in sedentary work (54.5%), not practicing regular exercise (77.0%) and not using hormone replacement therapy (87.5%).university education represent 47.0% of participated women Osteoporosis at any site represent 42.5%.Osteoporosis in forearm, spine and femur were (15. 7%, 32.0 %, 12.0%) respectively. According to MNA, women were classified into normal, at risk of malnutrition and malnourished (62.0%, 27.0%, 11.0 % respectively).By MUST they were classified into low risk, medium and high risk of malnutrition (73.0%, 1.5%, 25.5 % respectively). By univariate logistic analysis age and duration of menopause were significantly risk factors for osteoporosis while practicing regular exercise and intake of hormone replacement therapy were protective against osteoporosis. Other studied risk factors were not significantly related to osteoporosis. Presence of malnutrition or being at risk of malnutrition using either MNA or MUST was a significant predictor of osteoporosis. This relation was more prominent among elderly. Although there was a substantial (good) agreement between the three nutritional assessment tools (MNA, MNA-SF, MUST) in assessment of nutritional status of participants, their performance differed in prediction of osteoporosis. Area under the curve of MNA was greater that of MUST, and AUC of MNA and MUST were (0.850, 0.714) respectively. |