الفهرس 
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Abstract
Cesarean delivery is one of the most current surgeries
in women and one of the most significant challenges of
anesthesiologists in this kind of surgery is the fetuses`
exposure to anesthetic drugs. Regional anesthesia is
generally preferred during cesarean section, but general
anesthesia may be the only option under certain
circumstances such as patient preference, back deformities. A
safe induction agent for obstetrics should provide a smooth,
quick induction, maintain maternal hemodynamic function
and exert minimal to no effect on the Apgar score. The most
common drugs which are used in cesarean section to induce
general anesthesia are thiopental sodium and propofol.
This study conducted over 260 adult parturients, 20-35
years old, past 36 weeks gestation, scheduled for elective
cesarean section and has any contraindication for regional
anesthesia (e.g. patient’s refusal or back deformities) to
compare the effect of sodium thiopental induction versus
propofol induction on hemodynamics of mothers undergoing
elective cesarean section under general anesthesia and their
effect on Apgar score of their newborns. Maternal
hemodynamics at different stages of the operation were
assessed. Neonatal APGAR score was assessed and recorded
at 1, 5, and 10 minute after the umbilical cord was clamped.
Summary
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Umbilical cord venous blood gas analysis was also assessed
at 5 minute after the umbilical cord was clamped.
Our study reported a suppression of the hemodynamic
response to intubation more effectively with propofol than
thiopental. Regarding APGAR score, at 10 minute, 73
neonates (56%) in the thiopental group had an APGAR score
10 compared with 70 neonates (53,8%) in the propofol
group.
So, Apgar score does not differ significantly whether
thiopental or propofol is used for anesthetic induction in
women undergoing cesarean section under general anesthesia
but the use of propofol is more advantageous than thiopental
because it provides adequate anesthetic suppression of
pressor response of intubation without any depressive effect
on newborns.