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العنوان
Fasting Insulin Level Changes after Large Volume Liposuction /
المؤلف
Abdelaziz, Nermin Abdalazeem.
هيئة الاعداد
باحث / Nermin Abdalazeem Abdelaziz
مشرف / Hanna Habib Hanna
مشرف / Sarah Abdalazeem
مناقش / Sarah Abdalazeem
تاريخ النشر
2019.
عدد الصفحات
142p. :
اللغة
الإنجليزية
الدرجة
ماجستير
التخصص
جراحة
تاريخ الإجازة
1/1/2019
مكان الإجازة
جامعة عين شمس - كلية الطب - الجراحة العامة
الفهرس
Only 14 pages are availabe for public view

from 142

from 142

Abstract

O
besity is a disabling disease which has gained greater attention worldwide. It significantly increases the risk for other diseases such as diabetes type II.
Fasting insulin has been used as a surrogate measure of insulin sensitivity in studies of diabetes risk. Fasting plasma insulin concentration and insulin sensitivity are inversely related, i.e., that cross-sectionally, fasting insulinemia increases with increasing insulin resistance and vice versa.
The most common surgical procedure for obesity is liposuction. Liposuction is a closed technique that applies destructive energy to the subcutaneous tissue followed by aspiration of the emulsion. The usual energy is high-pressure vacuum pulling and avulsing fat through side openings in a hollow cannula. Alternative energy systems are powerassisted, laser-assisted, ultrasonic-assisted lipoplasty and radio-frequency-assisted.
Retained damaged tissue and bleeding may be a source for prolonged drainage and rare serious infection. Damage to connective tissue and neurovasculature reduction may prolong postoperative swelling and reduce the capacity for the skin to shrink down to the reduced volume. Inadequate contour improvement, sagging skin, and regain of weight are further problems.
Studies conflict on the medical improvement such as reduction of cardiac risk factors, blood pressure, and insulin levels. There are studies showing benefits of liposuction on cardiovascular risk factors, diabetes, and insulin requirements.
Liposuction is traditionally performed either as small-volume liposuction or large-volume liposuction. Large-volume liposuction which by definition is an aspirate of 5000 ml ,has been clinically shown to improve insulin sensitivity, fasting insulin levels in overweight and obese patients thus reducing their risk of developing type II diabetes, or beneficially improving their already manifest glucose intolerance.
Our study shows highly statistically significant decrease in fasting insulin between pre-operative and 3 months post-operative subsequently decrease the incidence of diabetes type II . The analysis of the study suggests that large volume liposuction surgery is considered aclinical therapy for obesity and its metabolic sequelae