الفهرس 
Mechanical ventilationOnly 14 pages are availabe for public view
 |  | from | 113 |  |  |
| | | from | 113 | | |
Abstract
Mechanical ventilation is the most widely used supportive therapy in intensive care units (ICU). Several forms of external support for respiration have been described to assist the failing ventilator pump and had constituted a major advance in the management of patients with respiratory distress. More recently, new noninvasive positive pressure ventilation (NIPPV) techniques, using patient/ ventilator interfaces in the form of facial masks, have been designed.
Noninvasive positive pressure ventilation (NIPPV) is one of the most important developments in respiratory medicine over the past 15 years and is increasingly used in many countries, but with a highly variable frequency of use.
NIPPV can facilitate weaning and reduce the duration of invasive mechanical ventilation, decrease complications, and reduce mortality compared to weaning on continued invasive ventilation.
The aim of this study is to clarify the role of non-invasive ventilation in preventing re-intubation if was used immediately following planned extubation in patients suffered respiratory failure in COPD patients and requiring invasive mechanical ventilation for 5 to 7 days.
The results of the study of the benefits of early use of non-invasive ventilation after extubation to limit probability of re-intubation.
Forty consecutive patients, who are invasively mechanically ventilated and classified as difficult to wean from the ventilator in the medical intensive care units of Ain Shams main university hospital between the 1st April and 1st of September 2018, were included.
The mean age in the present study for oxygen group was 56.20±5.56 years, while in NIPPV group was 57.75±5.17 years, 70% of patients in this present study were males.
The results of the study showed that:
APACHE II score, PaO2 and mean arterial blood pressure which might have a role in respiratory failure showed no statistically significant differences between both study groups.
Meanwhile, respiratory rate, heart rate and arterial blood gases showed high significance between both study groups
When predicting re-intubation as the endpoint between NIPPV (group A) and nasal cannula (group B); in this study resulted in lower rate of re intubation after planned extubation in the patients used non-invasive ventilation (group A) confirmed by the rate of re-intubated (25%) but in (group B) was 60%.
In conclusion, the use of NIPPV is associated with a marked reduction in the need for endotracheal intubation after planned extubation.