الفهرس | Only 14 pages are availabe for public view |
Abstract Poor management of postoperative pain is associated with delayed ambulation, pulmonary complications, and delayed transition to lower levels of care. It is important to manage complaints of pain adequately after hip surgeries. Pregabalin has been used for treatment of chronic pain, but recently it has been introduced in treatment of acute postoperative pain. This study is conducted to evaluate the postoperative analgesic effect of paracetamol and pregabalin combination versus paracetamol after hip surgeries. The study was done on 20 randomly chosen patients after approval of the medical ethical committee of Ain Shams University. Patients were divided randomly into two groups, each group consisted of 10 patients. After preoperative assessment and obtaining baseline vital data all patients received spinal anesthesia. group I received paracetamol 1gm intravenous immediately postoperatively and every 6 hours for 24 hours. group II received the same as group I plus two doses of oral pregabalin 300mg in the recovery room and 12 hours later. The two groups were adequately monitored and assessed postoperatively and they were compared regarding demographic data, postoperative pain control using numeric rating scale, sedation status using numeric sedation score, total pethidine consumption, hemodynamics and side effects. The result of this study revealed that combination of paracetamol and pregabalin as multimodal analgesia is better than paracetamol alone in postoperative analgesia, and decreasing use of opioids without significant effect on hemodynamics but with increased incidence of side effects such as somnolence, dizziness and blurred vision. |