الفهرس 
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Abstract
This study aimed to investigate the effect of tamarind seeds powder and alcoholic extract on hypercholesterolemic rats.
Thirty adult male albino rats, weighing 150± 10g were divided into six groups each with five rats. One of them was Negative Control Group, which fed on standard diet and tab water, and the other group was fed on standard diet 1.5% cholesterol + 0.5% bile salts for two weeks to induce hypercholesterolemia. This group was further divided into the following subgroups:
group 2: positive control group (untreated group).
group 3: Treated with 5% tamarind seeds powder.
group 4: Treated with 7.5% tamarind seeds powder.
group 5: Treated with alcoholic extract of 5% tamarind seeds powder.
group 6: Treated with alcoholic extract of 7.5% tamarind seeds powder.
At the end of experimental (28 days), the blood samples were collected after 12 hours fasting and serum was separated for determination of:
Lipid profile serum (total cholesterol (TC), triglycerides (TG), high density lipoprotein (HDLc), low density lipoprotein (LDLc), very low density lipoprotein (VLDLc), atherogenic index), Liver function (glutamic oxaloacetic transaminase (GOT), glutamic pyruvic transaminase (GPT), alkaline phosphates (ALP), kidney function (urea, creatinine, uric acid), and glucose. At the same time, the organs: kidney and liver were removed, washed in saline solution, dried by filter paper, weighted, and stored frozen in formalin solution 10% for histopathololgical examinations.
Statistical analysis:
The data were statistically analyzed using a computerized costate program by one way ANOVA. The results are presented as mean± SD. Difference between treatments at (p≤0.05) were considered significant.