الفهرس 
Gestational DiabetesOnly 14 pages are availabe for public view
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Abstract
Gestational diabetes mellitus is defined as the form of diabetes that occurs during pregnancy.
Women with gestational diabetes mellitus have a great degree of Insulin resistance compared to women without gestational diabetes.
Gestational diabetes has many complications that affect the mother and her foetus.
According to the foetus, macrosomia is the most importat consequence of gestational diabetes.
For the neonate, neonatal hypoglycemia is the most serious complication.
The pregnant woman is also affected during her pregnancy by the elevated blood sugar. She might face many complications such as: pre-eclamsia, preterm labour, polyhydramnios, postpartum haemorrhage, hypoglycemic episodes and finally, diabetic ketoacidosis.
For management of gestational diabetes, pregnant woman shall start with lifestyle changes as diet modifications and regular exercise. Others will need medications.
Insulin was the standard drug for treatment of gestational diabetes. It was known to be safe for both mother and foetus.
In the past, metformin was thought to be a teratogenic agent for the foetus, but in this study and also other previous studies, we proved that it is another safe choice for treatment of gestational diabetes as it is safe for mother and also for foetus.
In this study, we found that metformin is better than Insulin in controlling maternal and neonatal blood glucose levels, HbA1c, reduces maternal weight gain and also reduces the risk of foetal macrosomia.
According to our randomised controlled clinical trial, and by statistical analysis, metformin is better than insulin in treatment of gestational diabetes.