الفهرس 
Nocturnal EnuresisOnly 14 pages are availabe for public view
 |  | from | 168 |  |  |
| | | from | 168 | | |
Abstract
T
he 25-hydroxyvitamin D [25(OH)D] is the main circulating metabolite of vitamin D, and is considered to be an indicator of vitamin D status in the human body. Low 25(OH)D is considered to play an important role in the development of cardiovascular diseases, metabolic syndrome, type 2 diabetes mellitus, inflammatory and immune abnormalities, and sleep disorders. NE is a nighttime bedwetting (≥2times per week) in children five years of age or older. And The most common causes of it are arousal dysfunction and nocturnal polyuria. Arousal dysfunction is related to sleep disorders. Anatomic evidence and clinical studies suggest that vitamin D may be involved in sleep regulation.and its deficiency is associated with the severity of obstructive sleep apnea (OSA). Nocturnal polyuria is one of the main adverse outcomes of OSA. Moreover, vitamin D deficiency could directly lead to excessive urine production. Therefore, we propose the hypothesis that there is some connection between NE and vitamin D
The aim of work of this study is to investigate whether there is any relationship between 25 hydroxy Vitamin D and nocturnal enuresis in comparison to normal population.
We conducted this study on 80child fulfilling the inclusion criteria classified in to two groups: group1: 40 enuretic children,their ages ranged from 5-15 years old group2: 40 healthy, age and sex matched children as control group all patients and controls were subjected to full history, clinical examination, body measurements and face to face questionnaire, serum vitamin D by Elisa technique
We found that 75.5% of cases in the NE group had low Vit.D level (<20ng/ml) compared with 60% in the control group but this difference is not statistically significant and this is may be due to a small sample. In the current study, there was no significant difference between the cases and controls as regards low birth weight, family history, frequency of night-time bed wetting.
Also, there was no significant difference between both groups as regards the family educational level and stressed family pattern.
Considering the socio economic status; the NE group had a significantly higher family income than the control group
However, there was a significant difference between cases and controls as regards height and weight; where enuretic children were shorter than the healthy children. And had lower body weight