الفهرس 
Atopic Dermatitis
Diagnosis of atopic dermatitisOnly 14 pages are availabe for public view
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Abstract
Soy protein is an important component of soybeans and provides an abundant source of dietary protein. Food allergy to soy has been described in young children. This cross sectional study was carried out in the Pediatric Allergy and Immunology Unit, Children’s Hospital, Ain Shams University during the period from January 2017 to January 2018. It included 200 children aged between one and eighteen years with, physician diagnosed, atopic dermatitis.
About (3.5%, n: 7) of studied cases were positive to soya with mean diameter of soya wheal of (3) and a SD of (0.0) in positive cases, while (96.5%, n: 193) of cases were negative to soya. There was a statistically significant difference between soya sensitized patients and non-sensitized patients regarding diameter of soya wheal formation (P = 0.000).
There was a statistically significant difference between soya sensitized patients and non-sensitized patients regarding sensitivity to peach only detected by SPT (P-value 0.041), while it showed no statistically significant difference regarding house dust, egg white, cockroach, cow milk, Aspergillus, mango, banana, strawberry, fish and grass.
Patients involved in the study showed reactivity to multiple allergens; mostly for house dust (26.5%), Aspergillus (17.5%), egg white (12.5%), lesser percentages were for fish, peach and soy.
Generally, respiratory manifestations were the most common manifestations of allergic diseases (83%), followed by atopic dermatitis (22.5%). Soy has not been shown to be a common cause of severe/fatal reactions that only (0.5%, n: 1) of cases had history of anaphylaxis.
The majority (89%) of studied cases received oral steroids therapy and anti-histaminic medications (70.5%) for allergy control, while (49%) used mast cell stabilizers and (13.5%) of studied cases received local steroids.
Soy protein sensitization is not uncommon in children especially in those with atopic manifestations. We recommend large scale studies to evaluate the actual incidence of soy protein hypersensitivity in children in different age group.