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العنوان
Meta-analysis of Vitamin D
Supplementation trials in Deficient
Children Suffering from Obesity /
المؤلف
Nassar,May Fouad Shehata.
هيئة الاعداد
باحث / May Fouad Shehata Nassar
مشرف / Ehab Khairy Emam
مشرف / Mohamed Farouk Allam
تاريخ النشر
2019
عدد الصفحات
105P.:
اللغة
الإنجليزية
الدرجة
ماجستير
التخصص
طب الأطفال ، الفترة المحيطة بالولادة وصحة الطفل
تاريخ الإجازة
1/1/2019
مكان الإجازة
جامعة عين شمس - كلية الطب - طب الاطفال
الفهرس
Only 14 pages are availabe for public view

Abstract

The main objective of the current systematic review/metaanalysis
was to compare different results of vitamin D
supplementation in overweight/obese versus normal weight
children and adolescents. The secondary objective was to
compare the effectiveness of different supplementary doses of
vitamin D in obese Children.
Published clinical studies on vitamin D supplementation
in obese children and adolescents with vitamin D deficiency
were identified through a comprehensive MEDLINE/PubMed
search (from July 1966 till November 2017) using a variety of
Medical Subjects Headings and free text words: (vitamin D
AND supplementation AND clinical trials AND children AND
obesity). Outcomes intended after vitamin D supplementation
were improvement of vitamin D status, BMI alteration as well
as appetite changes.
Ten researches were retrieved but only six were relevant.
Further classification was done into meta-analysis I where
supplemented obese children and adolescents were compared to
non-obese controls and meta-analysis II where supplemented
obese children and adolescents were compared to matching
obese peers given placebo.
Pooled results from the six studies revealed significantly
lower vitamin D levels in obese compared to non-obese peers.Additionally, pooled risk from the two studies in meta-analysis
I that evaluated the number of obese and non-obese children
and adolescents who improved upon vitamin D
supplementation revealed that obesity poses a risk for not
receiving benefit from the vitamin D supplementation
disregards the dose or the duration of supplementation.