الفهرس 
STREPTOCOCCUS AGALACTIAEOnly 14 pages are availabe for public view
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Abstract
S
Treptococcus agalactiae (GBS) has been described as one of the commonest causes of the early onset of sepsis among the newborns, which leads to high rate of mortality and morbidity. 1t is found in the digestive, urinary, and reproductive tracts of males and females. A person who has the bacteria but shows no symptoms is said to be colonized, most pregnant women who are colonized with GBS have no symptoms or health effects. A woman who is colonized with GBS late in her pregnancy can pass it to her baby during labor resulting in early-onset GBS infections like meningitis or late- onset GBS infections such as pneumonia.
GBS screening late in pregnancy and treatment during labor can help to prevent GBS infections.
1f results of the screening test are positive, the pregnant female will receive treatment with antibiotics during labor to prevent GBS from being passed to her baby. The antibiotics work only if they are given during labor. 1f treatment is given earlier in pregnancy, the bacteria may regrow and be present during labor. Penicillin is the antibiotic that is most often given to prevent early-onset GBS infection in newborns.
This study aimed to examine the performance of Strep B carrot Broth as a one-step screening method for GBS versus Latex agglutination technique in near term pregnant females.
Our study was conducted during the period from December 2017 till March 2018 on 100 pregnant females between 35 -37 weeks of gestation attending the antenatal clinic of Obstetrics and Gynecology Department, Ain shams University Hospitals.
Duplicate vaginal swabs were taken from pregnant females, one swab inoculated into Strep B carrot Broth ™ and the other onto Todd Hewitt broth to be further tested by Latex agglutination technique.
All isolates were further identified by culturing on blood agar, Gram stain, catalase test, Streptococcus latex test, bacitracin test and CAMP test.
1t was found that the prevalence of GBS colonization was 33(33%) out of 100 vaginal swabs.
There was a statistically significant difference between culture on blood agar and Strep B carrot broth, SCB could detect 30 out of all 33 GBS cases.
Thirty three of consecutive specimens were found to be positive for GBS by either the latex agglutination method or the selective carrot broth method.
The carrot broth method was more sensitive than the latex method overall, GBS was detected in 30 of 33 (30 %) positive specimens by the Carrot Broth method, while the remaining 67 were confirmed to be negative.
Among 33 GBS isolates 30 (30%) were detected successfully by Strep B carrot Broth with 90%, 100% sensitivity and specificity respectively ™ while 23 (23%) were detected by Latex test with 67 %, 100 % sensitivity and specificity respectively.