الفهرس | Only 14 pages are availabe for public view |
Abstract Chronic sinusitis is one of the most prevalent chronic illnesses, affecting persons of all age groups. It is an inflammatory process that involves the paranasal sinuses and persists for 12 weeks or longer. It is almost always accompanied by concurrent nasal airway inflammation and is often preceded by rhinitis symptoms; thus, the term chronic rhinosinusitis (CRS) has evolved to more accurately describe this condition. CRS may manifest as one of three major clinical syndromes: CRS without nasal polyps, CRS with nasal polyps, or allergic fungal rhinosinusitis. These classifications possess a great deal of therapeutic significance. Patients with symptomatic CRS have a high prevalence of sleep pathology. The relationship between sleep dysfunction and quality of life (QOL) in CRS is likely bidirectional, whereby disability predicts worse sleep which may influence QOL. The aim of this study is to investigate the effect of chronic rhinosinusitis (CRS) on sleep disordered breathing. This study was conducted on one hundred patients with chronic rhinosinusitis attended to ENT departments of El- Maadi Armed Forces Medical Complex, Kobry El-Kobba Armed Forces Medical Complex and El-Demerdash hospitals.Additional 10 control patients were included in the study. Patients who were included in the study were divided into 3 groups as follows: Study group A: included 50 patients suffering from chronic rhinosinusitis with nasal polyposis +/- septal deviation. Study group B: included 50 patients suffering from chronic rhinosinusitis without nasal polyposis. Study group C: included 10 patients serving as control group with no sinonasal disorders and no other cause of sleep apnea. All of the study groups were subjected to the following measures preoperative: 1- Complete ENT history taking with particular emphasis on Epworth Sleepiness Scale questionnaires (ESS). 2- Full ENT examination. 3- Endoscopic examination of the nose and paranasal sinuses. 4- High resolution Sinonasal computed tomograghy (CT) scan. 5- Overnight polysomnography using (Nicolet) device in Neurology department in El-Maadi armed forces medical complex. All these findings were recorded one month postoperatively for all patients for evaluation.esults obtained from this study could be summarized as follow: Comparative study between the 3 groups revealed; 1- Non-significant statistical difference as regards age, gender and BMI 2- Highly significant increase in ESS score in ”A group”; compared to B then C groups. 3- Highly significant increase in moderate and severe ESS categories in ”A group”; compared to other groups Comparative study between pre and post-operative measurements revealed; 1- Highly significant increase in post-operative sleep efficiency, minimal and basal Spo2 measurements in ”A group”. 2- Highly significant decrease in post-operative snore index and snore episodic measurements in ”A group”. 3- Non-significant difference regarding (A+H) index measurements in ”A group”. from the previous results, it can be concluded that Surgery decreased snoring and ESS scores,increased sleep efficiency, minimal and basal Spo2 measurements without changes in the apnea-hypopnea index and improved sleep quality. |