الفهرس 
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Abstract
This study was conducted at Obstetrics and Gynecology department, Ain Shams University, maternity hospital and Al-Galaa maternity teaching hospital in the period of time from June 2017 to May 2018.
The aim of this study was to compare 50 μg of sublingual misoprostol to 50 μg of vaginal misoprostol for induction of labor at term regarding efficacy and safety.
The total number of patients studied was 104 patients, divided into two groups; the first group (V) included
52 patients who received vaginal misoprostol 50 μg every 6 hours for a maximum of 4 doses, the second group (S) included 52 patients who received sublingual misoprostol 50 μg every
6 hours for a maximum of 4 doses.
Sublingual misoprostol 50 μg administered at 6 hourly intervals is as effective in promoting cervical ripening and inducing labor as vaginal misoprostol 50 μg administered 6 hourly intervals as regarding induction to delivery interval, number of doses, shorter hospitalization and neonatal outcome. Sublingual misoprostol 50 μg has a higher maternal and perinatal safety profile than the vaginal 50 μg misoprostol including cesarean rates due to fetal distress, adverse maternal outcomes as hyperstimulation, so sublingual 50 μg misoprostol administered at 6 hourly intervals as an efficacious and safe option for labor induction, low cost and availability are its added benefits.