الفهرس | Only 14 pages are availabe for public view |
Abstract Vitamin D deficiency (<20 ng/mL) and insufficiency (20–29 ng/mL) are common among patients with end stage kidney disease on regular hemodialysis. As in the general population, this condition is associated with increased morbidity and poor outcomes. The benefit of native vitamin D supplementation remains debatable because observational studies suggest that vitamin D receptor activator (VDRA) use is associated with better outcomes and it is more efficient for decreasing the serum parathormone (PTH) levels. Vitamin D has pleiotropic effects on the immune, cardiovascular and neurological systems and on antineoplastic activity. This study was conducted to assess vitamin D level, 25(OH) D, in patients end stage renal disease on regular hemodialysis. This study included 100 HD patients randomly selected from dialysis unit in Ain Shams University hospital; it was found that 50% of patients have 25(OH) VIT D deficiency 34% are insufficient and only 16%, was sufficient.No significant correlation was found between 25(OH) VIT D serum level and hemoglobin level or iron profile. In the present study, we have assessed serum levels of PTH, Calcium, and Phosphorus without observing statistically significant correlation with vitamin D level. In this study, no significant differences observed between the drug doses of calcium acetate, alphacalcidol, erythropoietin and vitamin D level. |