الفهرس 
VITAMIN DOnly 14 pages are availabe for public view
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Abstract
The aim of this essay is to review the possible role of vitamin D in the pathogenesis and treatment of different rheumatic diseases. And Meta-analysis of rheumatoid arthritis
We performed a literature search for studies that examined vitamin D status in RA patients and controls and the relationship between serum vitamin D levels and RA activity
Our meta- analysis included only 6 studies according to our inclusion and exclusion criteria.
Inclusion criteria
- Predefined RA definition
- Data on serum vitamin D values in an adult population
Exclusion criteria
We excluded studies if:
- They contained overlapping or insufficient data.
- They were reviews or case reports.
- They were abstract only.
Our meta- analysis revealed that there is statistically insignificant difference in serum Vit D and frequency of Vitamin D deficiency between RA cases and control .Analysis of the correlation between serum Vit D and ESR in RA cases revealed negative statistically significant correlation and no correlation between serum Vit D and CRP and disease activity in RA patients.
Recommendations:
We need further clinical studies on a large number of patients for longer duration to investigate the change in serum vitamin D level and its relation with disease activity by serial measurements not a single one.