الفهرس 
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Abstract
This experimental study showed that Low Level Laser Therapy (LLLT) has a positive local biostimulative effect in the early stage of bone healing. Platelet Rich Fibrin (PRF) also has shown to be effective in the treatment of intrabony periodontal defects. The main objective of our experimental study was to demonstrate the combined effects of LLL T and PRF on bone healing. Our experimental study was done over 80 bony cavities in 20 adult male rabbits, aged 12 months. An incision was made for exposure of the femur bone of all rabbits. Then, by using a large round surgical bur, a perforated hole was made in the femur. The cavities induced in these rabbits were divided into 4 groups: (group I) Control group which was neither subjected to any laser irradiation nor filled with any bone substitute; (group II) Bony defects were filled with PRF;
(group III) Cavities were subjected to Low Level Laser (LLL) for biostimulation; (group IV) Cavities were subjected to LLL for biostimulation then were filled with PRF. Histolopathological assessment of the four groups were done by Haematoxyline and Eosin stain. Statistical analysis was done using ANOVA and Bonferroni tests for comparisons between the four groups. The area percentage of the newly formed bone in group IV is significantly higher than the other three groups. The area percentage of the newly formed bone in group III is significantly higher than group II. LLL T could induce bone formation in the bone defect at a faster rate than PRF. However combination of both LLL T and PRF as a treatment modality could induce bone formation in the bone defect more than that of LLL T or PRF alone.