الفهرس 
INTRODUCTIONOnly 14 pages are availabe for public view
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Abstract
Systemic lupus erythematosus is a systemic autoimmune disease in which the body’s immune system mistakenly attacks normal tissue. Angiotensin II is the main effector of the renin-angiotensin system. Angiotensin II binds and activates two major types of serpentine, seven transmembrane domain G-protein coupled receptors, namely AT1R and AT2R, and these two receptors carry little minimal similarities. This work is organized to investigate the effect of AT1R gene polymorphism at position (A1166C) and AT2R gene polymorphisms in exon 3 (C1593A) and intron 1 (A1675G) on the genetic susceptibility for systemic lupus erythematosus among Egyptian children. Subjects included in this case-controlled study constituted 123 cases presenting children patients of SLE which were selected from Outpatient’s Clinic of Mansoura University children’s hospital; Mansoura; Egypt. And 100 healthy children as controls.