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العنوان
Regenerative capacity of allogenic gingival margin-derived stem cells with fibrin glue on rats’ partially dissected submandibular salivary glands /
المؤلف
Abdel-Latif, Noura Hasan Mohammad.
هيئة الاعداد
باحث / نورا حسن محمد عبداللطيف
مشرف / محمد السيد هلال
مشرف / محمد العوضي جراوش
مشرف / محمد عبدالرحمن محمد
مناقش / عصام فاروق على سوسة
مناقش / محمد عبدالقادر صبح
الموضوع
Stem cells. Regeneration (biology) Adhesives. Biology. Salivary glands. Dentistry - Problem solving. Dental care.
تاريخ النشر
2017.
عدد الصفحات
115 p. :
اللغة
الإنجليزية
الدرجة
ماجستير
التخصص
Dentistry (miscellaneous)
تاريخ الإجازة
01/09/2018
مكان الإجازة
جامعة المنصورة - كلية طب الأسنان - oral Biology
الفهرس
Only 14 pages are availabe for public view

from 138

from 138

Abstract

Salivary gland malignant tumors are extremely variable in comparison to other malignancy types, including about 24 different subtypes. Although radiotherapy is considered the most damaging treatment modality to salivary glands, other modalities result in gland atrophy and hypofunction. Last stem cell researches in the dental field have detected a diversity of adult stem cell sources in the oral and maxillofacial region. GMSCs exhibit clonogenicity, self-renewal and a multipotent differentiation capabilityity similar to that of BM-MSCs. MSCs in fibrin glue(as a scaffold) have more efficient immune-regulatory properties. In contrast, MSCs within fibrin glue hardly migrate. In this study, gingiva-derived mesenchymal stem cells with fibrin glue caused reconstruction of partially dissected submandibular salivary gland in rats.