الفهرس 
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Abstract
Objective: The aim of the present study is to evaluate the efficacy of strontium ranelate as a bone graft substance in correction of alveolar bone loss associated with periodontal disease . Materials and methods: A split-mouth study will be used in all 20 patients. After scalling and root planning (SRP) , a full thickness flap will be done and a mix of strontium ranelate 2gm (Protelos) and sterile saline will be delivered in one side untill the bone defect is filled, and the other side will subjected only to SRP. At first Periodontal health statue will be assessed by measuring specific indices such as: Gingval index (GI), Periodontal pocket depth (PPD) ,Bleeding on probing (BOP) and Plaque index (PI). At baseline, digital panoramic radiograph will be taken, rescoring of all indices will be recorded after 2, 6 and 8 weeks, and a panoramic radiographs will be taken again after 12 weeks for radiographic assesement .Results: Comparing the PPD between the 2 sides showed that there was much improvement in the side where the strontium ranelate has delivered and (p value <0.05) so it is considered statistically significant. Panoramic xrays results: comparing two sides showed increase nearly about 1.5-2 mm in the hight of the alveloar bone in the side of strontium ranelate while the other side remained without any progression in the height of the alveolar bone. Conclusion: clinical and radiographic results obviously showed statistically significant and provides evidence that strontium ranelate can be used for management of alveolar bone loss assiociated with periodontal diseases.