الفهرس 
INTRODUCTIONOnly 14 pages are availabe for public view
Abstract
Traumatic brain injury (TBI) is a critical public health and socio-economic problem throughout the world. It is a major cause of death, especially among young adults, and lifelong disability is common in those who survive.
TBI is defined as “an alteration in brain function, or other evidence of brain pathol-ogy, caused by an external force.”
The most common cause of TBI all over the world is Road Traffic Accidents (RTA). These include injuries to vehicle occupants, pedestrians, motorcyclists and bicyclists.
Complications are distinct medical problems that may arise as a result of the TBI. The results of traumatic brain injury vary widely in type and duration; they include physical, cognitive, emotional, and behavioral complications
In recent years, the application of brain-specific markers of neuronal, glial, and axonal damage, identified in the peripheral blood, has shown potential clinical utility in neuro intensive care as diagnostic, prognostic, and monitoring adjuncts.
Glial fibrillary acidic protein (GFAP) is a monomeric intermediate filament protein found in the astroglial skeleton. Intermediate filaments form networks that provide support and strength to the cells. Several molecules of GFAP bind together to form the type of intermediate filament found in astroglia.
The aim of the present study was to assess the role of Glial Fibrillary Acidic Protein (GFAP) in the evaluation of patients of acute traumatic brain injuries admitted to the Emergency department of Alexandria Main University Hospital and to evaluate the applicability of Rotterdam computed tomography score in prediction of severity in patients of traumatic brain injury.