الفهرس 
Acknowledgements
Cardiac arrhythmiaOnly 14 pages are availabe for public view
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Abstract
Cardiac arrhythmia is often present in patients with acute coronary syndrome (ACS) and may be due to the electrolyte imbalance. One of the causes of mortality in acute myocardial infarction (AMI) is ventricular tachycardia. Electrolyte imbalance is one of the probable causes of ventricular tachycardia in patients with ACS.
A decrease in serum potassium (K) level has been suggested to be a fairly common observation in patients with acute coronary syndrome (ACS), which has been shown to increase the risk of cardiac events, including lethal ventricular arrhythmias. In addition, a decrease in K level generally induces vasoconstriction, which leads to further ischemia, thereby producing a vicious cycle.
Mg++ and/or K+ depletion can play a pivotal role in the genesis of cardiac arrhythmias, particularly in patients with underlying ischemic heart disease.
Arrhythmias could be due to concurrent hypokalemia, hypomagnesemia itself, or both. Mg++ has important electrophysiological effects; it plays a critical role in the regulation of energy sources and in the control of ion pumps, and it has a direct membrane stabilizing effect on excitable myocardial membranes without adversely affecting repolarization time
This study aimed to assess the prevalence and clinical significance of electrolyte imbalance (Potassium and Magnesium) in ACS and its relation with arrhythmia in early phases.
The study included all patients (registered) with Acute coronary syndrome > 18 years old admitted to CCU of Cardiology Department ,Assiut University Hospital .During the period from 1-10-2014 to 31-3-2015.(400 patients)
The study protocols are approved by the ethical committee of Assiut faculty medicine.
Inclusion criteria:
• Unstable angina.
• Non STEM1.
• STEM1.
• Recent attacks.
Exclusion criteria:
• Any chronic arrhythmia
• Ischemic cardiomyopathy on diuretic therapy.
• Renal diseases and renal impairment.
• Alcohol intake.
Serum potassium and magnesium levels were measured within the first few hours for patients with ACS admitted to CCU at Assiut University Hospital. Cardiac arrhythmias were documented using standard ECG and Continuous monitoring for most critical patients with arrhythmia or significant potassium or magnesium disturbance.
Moreover all patients were assessed by TIMI Risk Score