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العنوان
Some Pharmacological Studies
on Chlorella Vulgaris /
المؤلف
Fadil, Rehab Mohammed Ahmed.
هيئة الاعداد
باحث / رحاب محمد احمد فاضل
مشرف / سوسن محمد على الشيخ
مشرف / عزة أحمد عبدالغفار جلال
مناقش / سوسن محمد على الشيخ
الموضوع
Chlorella vulgaris.
تاريخ النشر
2018.
عدد الصفحات
99 p. :
اللغة
الإنجليزية
الدرجة
ماجستير
التخصص
البيطري
تاريخ الإجازة
1/1/2018
مكان الإجازة
جامعة الزقازيق - كلية الطب البيطرى - الفارماكولوجيا
الفهرس
Only 14 pages are availabe for public view

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from 126

Abstract

Deltamethrin is a broad-spectrum synthetic type II pyrethroid
currently used on crops and in public health application for malaria
control. Hepatotoxicity, nephrotoxicity and neurotoxicity are a common
side effects of DLM that is widely used as insecticide all over the world.
The main pathogenic mechanism following exposure to DLM appears to
involve the generation of reactive oxygen species.
There are many reports recommending that using of various
antioxidants might be effective in alleviating DLM induced toxicities in
different tissues.
Chlorella vulgaris contains very potent naturally occurring
antioxidant and free radical scavenging agents. One of the most important
properties of C. vulgaris is its antioxidant activity. Very high amounts of
beta-carotene, tocopherol and combined form of these antioxidants make
Chlorella a very good source of natural antioxidant along with high
protein. These antioxidants can protect the body from oxidative stress.
Therefore, the current study was delineated to evaluate the possible
hepatorenal and neuroprotective effect of C. vulgaris powder in
deltamethrin intoxicated rats.
For this purpose, thirty two adult male albino rats were randomly
allocated into four equal groups as follow:
group I, Control group, received 0.5ml distilled water orally once
daily for 8 weeks.
group II, Chlorella treated group (CV), received C. vulgaris
powder (35mg/ kg b.wt.) orally once daily for 8 weeks.