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Colorectal cancer is the most common GIT
malignancy all over the world with a mortality rate of 3,9%.
Over one-half of the patients who die of colorectal
cancer have liver metastases at autopsy , and the majority of
these patients die as a result of liver metastases.
The majority of patients with hepatic metastases are
not suitable for resection although the resection is the best
way of survival for a patient suffers from hepatic metastases
from colorectal cancer.
So patients who may benefit from this procedure must
be chosen carefully according to specific criteria. They
undergoes some non invasive imaging modalities like
computed tomography, positron emission tomography using
florine-18 labelled flurodeoxy-glucose and they receive
neoadjuvant ,adjuvant chemotherapy to improve the results
of the procedure.
Patients considered not suitable for the resection
according to number or distribution of liver metastases,
undergo systemic chemotherapy , and some other new
therapies such as portal vein embolization ,radiofrequency
ablation and cryosurgery.
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In conclusion , surgery is the most effective form of
therapy for CRLM .Recent advances in imaging modalities
have helped in better patients selection for surgery .Newer
chemotherapeutic agents and surgical and radiological
interventions have meant that an increasing number of
patients can now be considered suitable for surgical