الفهرس 
IntroductionOnly 14 pages are availabe for public view
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Abstract
This study was conducted on 30 full-term neonates ≥36 weeks of gestational age diagnosed with asphyxia and admitted to the neonatal intensive care unit (NICU), Minia University and Minia Insurance hospitals during the period of January 2013 to May 2014, and 20 controls. All the studied neonates were subjected to: 1. Maternal history taking.2. Detailed antenatal and perinatal history.3. Deliveries were attended, Apgar score was recorded at 1 and 5 minutes. Resuscitation was done when needed. clinical examination including: Gestational age assessment using Dubowitz score, anthropometric measures including weight, length and skull circumference, full clinical examination (chest , heart, abdomen……..) and detailed neurological examination and assessment of the grade of HIE using Sarnat and Sarnat classification.
4. Laboratory investigations including: CBC, CRP, ABG and SAA protein
At the time of hospital discharge, 14(46%) infants had normal neurological examinations and 13 infants were abnormal. Neurological abnormalities included decreased muscle tone, increased tone and abnormal reflexes.
Serum Amyloid A Protein (SAA) at day 1 was significantly higher in cases when compared with controls (P<0.001); within cases, SAA at day 1 was higher in those who died compared with those who survived. Summary and Conclusion SAA at day 1 correlated significantly with the severity grade of encephalopathy, negatively correlated with Apgar score at 1 min. and 5 min. and negatively correlated with initial pH values. SAA at day 7 significantly correlated with grades of encephalopathy and negatively correlated with pH values. SAA at day 1 did not associate with sex, mode of delivery, maternal age and birth weight.