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العنوان
Depression and Free Testosterone Levels
in Egyptian Obese Adolescents Males /
المؤلف
El Sawy, Nahla Mohamed Ali Mohamed.
هيئة الاعداد
باحث / Nahla Mohamed Ali Mohamed El Sawy
مشرف / Eman Amin Abdel Aziz
مشرف / Alaa Youssef Ahmed
مناقش / Noha Refaat Mohamed
تاريخ النشر
2017.
عدد الصفحات
213p. :
اللغة
الإنجليزية
الدرجة
ماجستير
التخصص
طب الأطفال ، الفترة المحيطة بالولادة وصحة الطفل
تاريخ الإجازة
1/1/2017
مكان الإجازة
جامعة عين شمس - كلية الطب - Pediatrics
الفهرس
Only 14 pages are availabe for public view

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Abstract

SUMMARY
hildhood obesity has reached epidemic levels in developed
as well as in developing countries. Overweight and obesity
in childhood are known to have significant impact on both
physical and psychological health.
Obesity in males, particularly when central, is associated
with lower total testosterone [TT], free testosterone [FT] and
sex hormone-binding globulin [SHBG], and a greater decline in
TT and FT with increasing age compared with lean males.
This study was a cross-sectional, case-control study
conducted on 60 Egyptian obese adolescents males collected
from the Pediatric Obesity Clinic, Pediatrics Hospital, Ain
Shams University, the Pediatric Obesity Clinic, Pediatrics
Hospital, Zagazig University and 3 high schools in Zagazig.
Sixty Age matched males without depression or obesity were
included to serve as controls and were collected from 3 high
schools in Zagazig.
All these adolescents were subjected to full history taking,
full clinical examination, laboratory investigation (free
testosterone, estradiol, FSH and LH), Tanner staging, blood
pressure measurement and psychological assessment for
depression using Center for Epidemiological Studies Depression
Scale for Children (CES-DC), Children’s depression inventory
(CDI) and Mini International Neuropsychiatric Interview for
Children and Adolescents (MINI-KID).
C
Summary 
145
The study revealed that obesity is associated with higher
incidence of depression in adolescent males where (60%) of
obese adolescent males had mild depression and (6.7%) of
them had moderate depression, while all non obese adolescent
males (100%) were not depressed.
Also, there was a significant difference in mean free
testosterone levels between obese adolescents with depressive
symptoms and obese adolescents without depressive symptoms
where the mean of free testosterone levels was lower in obese
adolescents who had the following depressive symptoms: feeling
depressed, eating disorders, sleeping disorders, feeling restless,
feeling guilty, poor concentration and suicidality, while the mean
free testosterone level was higher in obese adolescents who had
the following depressive symptoms: loss of interest and feeling
tired.
Also, there were negative significant correlations
between mild, moderate depression (according to CDI) and
hormonal levels of free testosterone in obese adolescents males
and there were significant negative correlations between free
testosterone level and the following depressive symptoms
(according to MINI-KID module A); feeling depressed, eating
disorders, sleeping disorders, feeling restless, feeling guilty, poor
concentration and suicidality, while there were significant
positive correlations between mean free testosterone level and
the following depressive symptoms; loss of interest and feeling
tired