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العنوان
Quality Of Life, Fatigue, Changes In Insulin Like Growth Factor 1, Bone Mineral Density And Muscle Mass In Elderly Patients With COPD /
المؤلف
Hussein, Hazem El Sayed.
هيئة الاعداد
باحث / حازم السيد حسين
مشرف / معتصم صلاح عامر
مشرف / راندا عبدالوياب رضا مبروك
مشرف / شيريو مصطفي موسي
مشرف / يهد محمود طٌ
تاريخ النشر
2017.
عدد الصفحات
169.p :
اللغة
الإنجليزية
الدرجة
الدكتوراه
التخصص
طب الشيخوخة وعلم الشيخوخة
تاريخ الإجازة
1/1/2016
مكان الإجازة
جامعة عين شمس - كلية الطب - GeriatricMedicine
الفهرس
Only 14 pages are availabe for public view

from 179

from 179

Abstract

Backgroud: COPD is a highly prevalent systemic disease in the elderly population and it is considered as a major health problem in Egypt, However information on its prevalence, morbidity, and mortality is still lacking.COPD has a variety of extrapulmonary manifestations and our study was conducted to determine the changes in insulin like growth factor-1, Bone mineral density and muscle mass in elderly people with COPD.
Material and Methods: case control study conducted on 90 elderly participants and they were classified into two groups:
Cases Group:
Forty five patients diagnosed to have COPD either mild or moderate.
Control Group:
Forty five healthy subjects, age and gender matched to cases recruited from the community Both groups were subjected to detailed history taking and clinical examination, comprehensive geriatric assessment, spirometry , measurement of serum IGF-1, DXA scan to determine BMD and muscle mass.
Results: The study showed that elderly COPD patients had a lower level of IGF-1 (106.1) compared with control group (184.6) which is lower by 42%and a lower BMD in the cases group (1.15) compared to the control group (1.52) and also a lower muscle mass (47465) when compared to normal elderly(49400).
Conclusion: the study concluded that COPD patients had a lower mean level of IGF- 1, BMD and Muscle mass than normal elderly.
Keywords: COPD, BMD, IGF, Muscle mass, Fatigue