الفهرس 
List of abbreviations
OligodendrocytesOnly 14 pages are availabe for public view
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Abstract
In the present study, we investigated the ability of human OBNSCS to differentiate into oligodendrocytes using RT-PCR and immunocytochemistry. In the presence of fetal calf serum, all-trans retinoic acid (RA), triiodothyronine (T3), and cyclic adenosine monophosphate (cAMP), OBNSCS were differentiated into oligodendrocytes precursors as evidenced by induction and repression of NG2 and nestin genes, respectively. These finding were confirmed at the protein level using fluorescent immunocytochemistry (ICC) according to standard protocol. Taken together, the present study highlighted the ability of OBNSC to differentiate into oligodendrocytes, a finding that indicate their possible use as a promising candidate for cell-based therapy for neurodegenerative and traumatic diseases associated with myelin impairments.