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العنوان
Utility of Hydrazines in The Synthesis of Some
Heterocycles /
المؤلف
Samir,Sandy Samy.
هيئة الاعداد
باحث / Sandy Samy Samir
مشرف / Ahmed Said Ahmed Youssef
مشرف / Magdy Mohamed Hemdan
مشرف / Wael S. I. Abou El-Magd
تاريخ النشر
2016
عدد الصفحات
306p.;
اللغة
الإنجليزية
الدرجة
ماجستير
التخصص
Inorganic Chemistry
تاريخ الإجازة
1/1/2016
مكان الإجازة
جامعة عين شمس - كلية العلوم - كيمياء
الفهرس
Only 14 pages are availabe for public view

Abstract

Derivatives of thiosemicarbazide are a class of organic compounds
that were found to be associated with various biological activities . They are
known to exhibit antifungal , anti-inflammatory, anti HIV and herbicidal
activities . Moreover, they are used as corrosion inhibitors of steal and
semiconductors , in addition to their uses in the metal complexes .
Thiosemicarbazides are versatile compounds, which have been extensively
used in the synthesis of different heterocyclic ring systems .
The original work of this thesis can be classified into three parts:
Part 1: In this part, the synthesis of acyl thiosemicarbazides 1-(2-Benzamido-
3-arylacryloyl)-4-dodecanoyl thiosemicarbazides and 1-(2-
benzamido-3-arylacryloyl)-4-phenyl- thiosemicarbazide and their
cyclization with different reagents in different media are described.
Part 2: The antimicrobial activities of the synthesized compounds were
examined against two types of bacteria and two types of fungi.
Part 3: In this part, comparative study between the reactivity of Z- and Eisomers of 2-benzamido-3-phenylacrylohydrazide towards some
carbon electrophiles was discussed.