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العنوان
The Effect of stem cell application on bone
Regenerate during distraction osteogensis
An Experimental Study
المؤلف
El Hadidi,Yasser Mohamed Nabil Ahmed Khirat
هيئة الاعداد
باحث / ياسر محمد نبيل الحديدى
مشرف / صلاح عبد الفتاح احمد
مشرف / مروة عبد الوهاب القصبى
مشرف / سيد بكرى أحمد
الموضوع
Qrmak
تاريخ النشر
2015
عدد الصفحات
(112) p
اللغة
الإنجليزية
الدرجة
ماجستير
التخصص
Oral Surgery
تاريخ الإجازة
1/1/2015
مكان الإجازة
جامعة عين شمس - كلية طب الأسنان - جراحة فم
الفهرس
Only 14 pages are availabe for public view

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Abstract

The purpose of this study was to investigate the added effect of MSCs
application in the distraction gap to improve bone quality. This study was
conducted on fourteen young goats with average weight. Animals were
equally divided into two groups; study and control group. The study group
undergone the process of distraction osteogenesis aided with MSCs
application whereas the control group undergone the distraction osteogenesis
with no addition of MSCs. Both groups received distraction at rate one
millimeter per day after seven days of latency period. In the study group;
MSCs were applied (3 million cells) on two doses every 10 days, both study
and control groups had 30 days of consolidation followed by sacrifice.
Animal were examined clinically through the study. Samples were
dissected from the animal cadavers after sacrifice to be assessed
radiographically by cone beam computed tomography to assess distracted
bone three dimension and bone density and histomorphometric assessment of
bone samples stained by H&E and Trichrome Masson stain. Results were
tabulated and assessed by independent sample T-test to assess statistical
significance; Cohen’s d to assess sample size and concordance correlation
coefficient to measure to assess the interexaminer error of assessment.