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Delirium is a common and serious disorder with high morbidity and mortality. It is often unrecognized and inadequately treated, and this may lead to poor outcome. There may be many reasons that delirium goes undetected, such as not understanding full pathophysiology and not having enough diagnostic tools to detect delirium in the early phase.
In the current study we examined 90 elderly patients divided into 45 delirious and 45 non delirious in a case control study to explore association between PCT and delirium.
In the current study age was risk factor for delirium, however gender, marital status, educational level and smoking history were not risk factor for delirium.
There was no significant association between co morbidities and delirium apart of CLD that was slightly more frequent among case group.
In the current study hypoglycemia, dehydration, stroke, hepatic encephalopathy, hypertensive encephalopathy and hyperosmolar hyperglycemic state were causes of delirium.
Depression was not risk factor for delirium while decrease functional status, infection, high ESR and high APACHEII score were risk factor for delirium.
PCT showed Significant and independent association with delirium suggesting that inflammation play a role in pathogensis of delirium. PCT level elevated in delirium regardless of cause of delirium. But it was not different across subtypes of delirium.
In the current study hypoactive delirium was the most common type of delirium, there was no significant difference between types of delirium as regard age, marital status, educational level and smoking history.
There was no significant difference between types of delirium regarding co morbidities. As regard cause of admission hypoglycemia was significantly most frequent among hypoactive type and dehydration was significantly most frequent among mixed type.
There was no significant difference between types of delirium as regard total APACHE II score, mortality, SIRS and depression.
In the current study ESR was significantly associated with delirium and this association significantly highest among mixed group and least among hyperactive group.