الفهرس 
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Abstract
The present thesis includes five chapters and the contents are subdivided into introduction, experimental as well as results and discussion.
Chapter I:
This chapter includes a literature survey for the important studies of Schiff base ligands, their metal complexes, nano-particles and nano-coordination chemistry.
Chapter II:
This chapter includes a detailed account about the experimental procedures and methods of preparation of Schiff base ligands and their complexes with metal ions [ Co(II), Ni(II), Cu(II) and Zn(II)], also preparation of nano-particles and nano-metal complexes. Finally the working procedures and the apparatus (molar conductance, IR, 1HNMR, UV-Vis, ESR, magnetic susceptibility TGA – DrTGA, biological and anticancer activity) are discussed.
Chapter III:
This chapter contains the results of studying the organic Schiff base ligands together with their discussion; it is subdivided into four parts:
1. The first part comprises a study of infrared absorption spectra of all organic molecules under investigation and the main bands are reported. A satisfactory band assignment is given and interpreted in some details using statistical method.
2. The second part comprises a study of the electronic absorption spectra in some organic solvents (e.g. DMF, EtOH, MeOH, Dioxan)
3. In the third part, the 1HNMR, spectra of the organic compounds under investigation are assigned and interpreted.
4. The last part includes mass spectra for one of the Schiff base ligands. Mechanisms of fragmentation patterns leading to different ions are discussed and interpreted.
Chapter IV:
This chapter includes the results of studying the metal complexes which contain new Schiff base ligands with their discussion, it includes the following:
1. The results of elemental analysis (C, H, N, S and M) and molar conductance measurements of the complexes under investigation in DMF solution.
2. The infrared absorption spectra (IR) of all metal complexes under investigation are recorded in the solid state as KBr discs. The important bands are assigned and identified. The shifts in band position and disappearance of the various OH- bands or their obvious decrease in relative intensity showed that the metal ion is coordinated to the ligand through the azomethine nitrogen and the oxygen of the hydroxyl group. Also the metal showed covalent bond with the oxygen of the hydroxyl group after its deprotonation. The statistical relation between Taft constant (σ*) and some functional groups of these complexes are carried out. It is found that the electron density around the metal ions are dependent on the ionization potential (Ip) and the radius of the metal ion used.
3. The results of thermal analyses (TGA – DrTGA) of some metal complexes to identify coordinated or lattice water or ethanol and the thermal stability of these complexes. Also the thermodynamic parameters of the complexes were determined.
4. The magnetic moment of the metal complexes under investigation are determined to give some information about the geometrical structure of these metal complexes.
5. The electronic spectra of all metal complexes in DMF solutions are discussed and assigned in order to gain some information about the geometry around metal ions. The data showed that some complexes have octahedral geometry and some complexes have square plannar geometry. The data confirmed the results obtained from the magnetic moment study.
6. The results of electron spin resonance (ESR) of the metal Schiff base complexes in solid state, in order to throw more light about the geometry of the complexes under investigation. The results were in agreement with those gained from both electronic system and magnetic moment determination.
7. 3D Molecular modeling study was reported to gain better insight on the molecular structures of ligands and some of their metal complexes.
8. The ligand and some complexes showed antimicrobial activity against selected kinds of bacteria, yeast and fungi. Also, they showed anticancer activity.
Chapter V:
1. Nano particles and nano Schiff base-complex were synthesized and characterized by scanning electron microscope SEM, UV-Vis and ESR spectra and their biological activities and anticancer evaluation were studied. They are antibacterial and anticancer materials.