الفهرس 
IntroductionOnly 14 pages are availabe for public view
 |  | from | 116 |  |  |
| | | from | 116 | | |
Abstract
The present study included 48 adults of OSA patients presented to the Otolaryngology and Rheumatology Departments in the Suez Canal University Hospital. All patients were subjected to assessment protocol, clinical examinations and electrophysiological studies of hypoglossal nerve.
The mean age of the patients was 42.6±10.5 years with the range of 28-57 years. The mean BMI of the studied patients was 32.8±3.4 kg/m2 with a range of 24-37 kg/m2. The majority of the studied patients were obese (n=39; 81.25%).
The majority of the patients had nasal obstruction (62.6%); 18.8% had unilateral obstruction and 43.7% had bilateral obstruction. Also, the majority of the patients had daily snoring (81.2%), while 18.8% of them had positional snoring.
Most of the patients had moderate to severe AHI (45>30) with a prevalence of 87.5%. The mean AHI of the patients was 27.1±8.98 with the range of 10-40. The degree of excessive daytime sleepiness was slight in 18.8% of the patients, mild in 50% of the patients and moderate in 31.3% of the patients. FTP grades were ranged from grade II (FTP II) (37.5%) to grade III (FTP III) (62.5%).
Most of the patients had delayed distal latency of hypoglossal nerve (75% of the patients in right and left hypoglossal nerves). The mean left distal latency of the patients was 3.24±1.23 ms with the range of 2.5-7.7 ms, while the mean right distal latency of the patients was 3.02±0.61 ms with the range of 2.4-4.6 ms. All the patients had low motor amplitude of hypoglossal nerve (100% of the patients in right and left hypoglossal nerves). The mean left motor amplitude of the patients was 1.68±0.61 mV with the range of 0.6-2.5 mV, while the mean right motor amplitude of the patients was 1.52±0.79 mV with the range of 0.6-3.2 mV.
There were significant positive correlations between excessive daytime sleepiness and BMI, snoring, FTP, Mallampati grading and right distal latency. There were significant positive correlations between AHI and age and BMI. There were significant positive correlations between FTP and age, BMI, snoring, excessive daytime sleepiness and Mallampati grading. There were significant positive correlations between Mallampati grading and age, BMI, snoring, AHI, excessive daytime sleepiness, FTP, right distal latency and right amplitude.
In conclusions:
• OSA patients have NCS findings suggestive of a hypoglossal mononeuropathy that include:
o Most of the patients (75%) had delayed distal latency.
o All the patients (100%) had low motor amplitude of hypoglossal nerve.
• There were significant positive correlations between:
o Excessive daytime sleepiness and BMI, snoring, FTP, Mallampati grading and right distal latency.
o AHI and age and BMI.
o Mallampati grading and age, BMI, snoring, AHI, excessive daytime sleepiness, FTP, right distal latency and right amplitude.
o BMI and age, snoring, AHI, excessive daytime sleepiness, FTP and Mallampati grading.