الفهرس 
Introduction
Anatomy of the BreastOnly 14 pages are availabe for public view
 |  | from | 170 |  |  |
| | | from | 170 | | |
Abstract
Conventional imaging modalities as mammography and
ultrasound remain the method of choice for routine screening
programs and is the 1P
st
P imaging aid, but conventional assessment
have well-known limitations, such as inaccurate differentiation
between benign and malignant lesions and estimation of the
size of malignant tumors.
The sensitivity of breast MRI for the detection of cancer is the
greatest of all imaging techniques and when the findings of
conventional imaging are inconclusive (i.e. BI-RADS 0), MRI can
be used as a problem-solving modality, it is also better at
identifying the true extent of cancer when multifocal disease or
ductal carcinoma in situ is present. However its reported
specificity is variable.
DWI if further clinical evaluation is needed represents an
easy non time consuming inexpensive complementary quantitative
breast imaging sequence. In addition, ADC mapping based on
diffusion properties provides valuable information on benign and
malignant lesions by characterizing tumor cellularity.
When the sensitivity of the MRI was high, its specificity was
low due to overlap in features of benign and malignant lesions.
DWI had higher specificity and the ADC value was a sensitive and specific parameter in differentiating benign and malignant
breast lesions. The specificity was higher for mass than non mass
lesions.
In Conclusion :
It must be understood that DWI should be conjugated
with DCE-MRI to avoid non visualization of small breast lesions,
in this way it may improve the specificity of MRI for
characterizing breast lesions. Moreover, DWI can be used alone in
combination with T2WI for cases in whom contrast agent could
not be given (e.g. pregnancy, renal dysfunction and those who
have sensitivity against contrast agent). Thus, it is recommended
as a part of routine preoperative examination. However; it is only
of moderate value in assessment of non mass breast lesions.