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العنوان
EFFECT OF ENVIRONMENTAL FACTOR ON BLOOD LEAD IN INFANTS :
المؤلف
Mosa, Mohamed Salem Anwar.
هيئة الاعداد
باحث / Mohamed Salem Anwar Mosa
مشرف / Farida EL-Baz Mohamed EL-Baz
مشرف / Azza Mohamed Youssef Abdel Aziz
مناقش / Mohamed EL-Sayed Mohamed Mowafy
تاريخ النشر
2014.
عدد الصفحات
174 p. :
اللغة
الإنجليزية
الدرجة
ماجستير
التخصص
طب الأطفال ، الفترة المحيطة بالولادة وصحة الطفل
تاريخ الإجازة
1/1/2014
مكان الإجازة
جامعة عين شمس - كلية التمريض - Pediatrics
الفهرس
Only 14 pages are availabe for public view

from 174

from 174

Abstract

Exposure to lead causes a variety of health effects, and affects children in particular. Too much lead can damage various systems of the body including the nervous and reproductive systems and the kidneys, and it can cause high blood pressure and anemia. Lead accumulates in the bones and lead poisoning may be diagnosed from a blue line around the gums. Lead is especially harmful to the developing brains of fetuses and young children and to pregnant women. Lead interferes with the metabolism of calcium and Vitamin D. High blood lead levels in children can cause consequences which may be irreversible including learning disabilities, behavioral problems, and mental retardation. At very high levels, lead can cause convulsions, coma and death.
People are exposed to lead through the air they breathe, through water and through food/ingestion. Toxic effects are usually due to long term exposure. The population groups at greatest risk of exposure are young children and workers. A recent report suggests that even a blood level of 10 micrograms per decilitre can have harmful effects on children’s learning and behavior. People can be exposed to lead contamination from the motor vehicle exhaust of leaded gasoline, as well as from industrial sources such as smelters and lead manufacturing and recycling industries, from cottage industry uses and waste sites.
Our study was undertaken to evaluate the effect of environmental lead exposure on the serum lead level in infants, breast fed and artificially fed in Suez governorate, Egypt.
60 healthy infants were included in this study, aged 3-9 months, 30 infants are living in Arab Almamal G1 {industrial area} [50%] 15 of them are artificially fed GIAF [25%] other 15 are breast fed GIBF [25%], and 30 infants are living in Alganayen G2 {rural area} [50%] 15 of them are artificially fed GIIAF [25%] other 15 are breast fed GIIBF [25%].
Complete blood picture and blood lead level to the studied infants, BLL measured by using Graphite Furnace Atomic Absorption Spectrophotometry by using 1.5 ml heparinized sample.
The current study showed that there’s no significant differences in hemoglobin level, RBCs count, white cells count and platelets count between infants live in Arab Almaamal G1 and infants live in Alganayen G2, that’s mean no effect of environmental lead exposure on CBC parameters in infants regardless type of feeding.
But there was a significant increase of serum lead level (BLL) in Arab Almaamal cases G1 in relation to Alganayen G2 mean a significant effect of environmental lead exposure on blood lead level in infants.
Also present study showed a significant increase of blood lead level (BLL) in artificially feeding cases (AF) in relation to breast feeding cases (BF) mean breastfeeding decrease effect of lead in infant body.
In our study no differences between artificial feeding and breastfed infants as regard CBC parameters, mean no significant effect of type of feeding on RBCs count, hemoglobin level or other blood component.
Our study showed a significant –ve correlation between RBCs count & BLL and a significant –ve correlation between HB & BLL, but no significance with other parameters, mean decrease hemoglobin level and RBCs count cause increase blood lead level or more lead in infant blood cause decrease hemoglobin level.
Other findings in our study are:
- A significant increase in blood lead level with the increase of amount of fed in CC.
- In the other hand there’s a significant decrease in blood lead level with increase or delayed age of weaning.
The current study showed
- Neurological deficits are more in areas of more environmental exposure of lead regardless the type of feeding either breast or artificial fed.
- Neurological deficits are more in artificial fed infants in relation to breast feeding infants regardless where live.