الفهرس 
HypoglycemiaOnly 14 pages are availabe for public view
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Abstract
Background: CKD patients are prone to episodes of hypoglycemia during
hemodialysis, a condition that can cause severe health complications
including dizziness, disorientation, slurred speech, and convulsions.
Diabetes is the most common cause of kidney disease and managing
diabetes in CKD patients can be complicated. Patients, who have diabetes
and have CKD with reduced GFR, frequently have lower insulin
requirements, reduced renal gluconeogenesis and prolonged half-life of antidiabetic
drugs.
Methods: 200 randomly selected patients with end – stage renal disease on
regular hemodialysis were included in this study during the period form 1st
of June 2011 till 30th of November 2011. Patients were fasting 2 hours
before the session and 2 hours on the session, not receiving IV fluids or
glucose. Random blood glucose readings were taken at zero time and after 2
hours on the hemodialysis session or with the development of symptomatic
hypoglycemia. Data were analyzed in correlation with epidemiologic
profiles, underlying etiologies and co-morbidities.
Results: Hypertension and diabetes mellitus were underlying etiology of
majority of cases. Less than one quarter of the patients experienced an
episode of hypoglycemia during hemodialysis, with most of them aged
between 40 – 60 years, having type 1 DM, cardiovascular disease
comorbidity and lower HGB level, as compared to the non-hypoglycemic
group.
Conclusion: CKD patients on regular hemodialysis are at a significant risk
for the development of hypoglycemia with or without the presence of
diabetes, but the risk is greatest in patients with CKD and diabetes.
Key words: End Stage Renal Disease, CKD, Hemodialysis, Diabetes
Mellitus, Hypoglycemia.