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العنوان
Sperm Chromatin Condensation Assay in
Varicocele Patients Before and After
Varicocelectomy\
المؤلف
El-Beltagy, Ahmed Atef.
هيئة الاعداد
باحث / Ahmed Atef El-Beltagy
مشرف / Ahmad Ibrahim Rasheed
مشرف / Mahmoud Abdel-Rahim Abdallah
مناقش / Mahmoud Abdel-Rahim Abdallah
تاريخ النشر
2014.
عدد الصفحات
146. :
اللغة
الإنجليزية
الدرجة
ماجستير
التخصص
الأمراض الجلدية
تاريخ الإجازة
1/1/2014
مكان الإجازة
جامعة عين شمس - كلية الطب - جلدية
الفهرس
Only 14 pages are availabe for public view

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from 146

Abstract

SUMMARY AND CONCLUSION
The Study was performed including 20 male patients
had clinically palpable and ultrasound proved varicocele
(study group) and 10 subjects as control group with ages
ranging from 18 to 45 years .The aim of the study to explore
impact of varicocele on sperm DNA integrity as an important
indicator of sperm maturation .
We found that preoperative sperm count in the patient’s
group ranged from 4 million per cc to 50 million per cc while
in the control group ranged from 20 to 150 million per cc ,
preoperative progressive motility ( a+b) in the patient’s group
ranged from 5 % - 30 % in the control group ranged from 34
% to 55 % .
We found significant difference between preoperative
and post operative DFI (P<0.05) in patient’s group.
The present study showed negative correlation
(r =-0.439) could be shown between preoperative motility and
baseline DFI while no correlation could be shown between
age, preoperative sperm count, morphology, varicocele
diameter and baseline DFI.
There was positive correlation could be shown between
the change of progressive motility postoperatively and the
Summary and Conclusion
- ٩٣ -
change of DFI (r = 0.504) while no correlation could be shown
between change of sperm count and DFI change (r = 0.51).
Based on our study we could suggest another way of
contribution of varicocele to male infertility by affecting DNA
integrity and increasing percentage of DNA fragmentation.
Further studies on DFI in varicocele may be recommended
on larger number of patients and with longer term follow up
periods.